The goal of this project is to develop an interactive, Web-based
Prognostigram Program for adult patients with newly diagnosed cancer.
The prognostic program will create individualized survival curves based on the
Cox Proportional Hazards model of survival data from Barnes-Jewish Hospital (BJH)
Oncology Data Services (ODS) and SEER*Stat (National Cancer Institute, Surveillance,
Epidemiology, and End Results Software package). The BJH ODS dataset has
comorbid health status information. Unfortunately, the SEER*Stat program
does not contain comorbid health information. To add the impact of
comorbid health information to the SEER*Stat dataset, the Investigators
will determine adjusted hazard ratios (i.e., adjusted for other important
prognostic factors) for comorbidity from the BJH ODS database. Adjusted survival
curves will be generated which take into account the impact of comorbid health
information. The survival curve for cancer patients will be presented on the
same figure as the survival curve for age, gender, and race-matched peers. This
program will reside on a password-protected server at the Washington University
Medical School Network Services.
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